We have witnessed unsettling global developments in infectious diseases, such as antibiotic-resistant infections, the resurgence of almost eradicated diseases, increasingly nerve-wracking pandemics arising in East Asia, and an expansion of tropical diseases to the U.S. mainland. Not surprisingly, employers are being forced to deal with a variety of workplace infections and illnesses. All employers would be wise to educate and prepare for the occasional odd disease challenge, much as do healthcare employers.